The recommended daily amount of vitamin A from all sources is 700 mcg/RE for women and 900 mcg/RE for men. When taken in excess of 3000 mcg/RE, vitamin A can cause birth defects. If you are pregnant, or considering becoming pregnant, do not take vitamin A supplements without consulting your doctor or pharmacist. This product contains selenium, which is toxic in high doses. A daily dose of 150 mcg for adults of selenium from dietary supplements should not be exceeded. Vitex agnus-castus may affect hormones and medicines such as oral contraceptives. Consult your health professional before use. Vitamin and mineral supplements should not replace a balanced diet. Always read the label and follow the directions for use.